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Dosing Guide for SGLT2 Inhibitors and GLP-1-based Medications for Type 2 Diabetes

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Updated: 10/21/26

Key dosing information for SGLT2-I and Incretin Mimetics (GLP-1 RAs and GLP-1 RA/GIP) including dose escalation, pen and needle RX considerations, proven benefits for ASCVD, CKD, HFrEF, HFpEF, and DKD.
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Support for The Michigan Collaborative for Type 2 Diabetes (MCT2D) is provided by Blue Cross Blue Shield of Michigan as part of the BCBSM Value Partnerships program.

Although Blue Cross Blue Shield of Michigan and MCT2D work collaboratively, the opinions, beliefs and viewpoints expressed by the author do not necessarily reflect the opinions, beliefs and viewpoints of BCBSM or any of its employees.